It depends on a few things and it might sound a bit confusing but theres IBL (inbred lines aka pure breeds, the pedigrees of weed strains), normally oldschool strains and landraces that haven't been tainted by other strains for many years, which are normally stable and sibling plants will be very similar to eachother.
Then theres polyhybrids, which are a mixture of unstable crosses all mixed together, wide variety of different sizes, smells and looks because of the broader genepool.
At the end of the day it's just pollen chucking, but if you want true f1 hybrids which tend to be uniform and vigorous, you will need to cross 2 ibl lines together.
If you don't mind sifting through different phenotypes (physical traits of said cross) you can just dump pollen on random crosses and it will be fine too.
Super Skunk is basically just Afghan × Skunk, being an old strain its more than likely been stabilised throughout the years, meaning uniform traits. A good candidate for chucking if you're after more uniform results